Publications

Elmore Lab Publications from Wellesley

(Elmore Lab undergraduate co-authors are underlined and corresponding authors are denoted by an asterik.)

Beers, M.; Hall, M. L.; Matthews, A. G.; Elmore, D. E.; Oakes, E. S. C.; Goss, J. W.*; Radhakrishnan, M. L.* “A Fully Integrated Undergraduate Introductory Biology and Chemistry Course with a Community-Based Focus. II. Vision, Design, Implementation, and Development.” Biochemistry and Molecular Biology Education202149, 859-869.

Pociask, S.; Weerapana, A.; Taylor, P.; Radhakrishnan, M. L.; Oakes, E. S. C.; Matthews, A. G.*; Elmore, D. E.* “A Fully Integrated Undergraduate Introductory Biology and Chemistry Course with a Community-Based Focus. II. Assessment of Course Effectiveness.” Biochemistry and Molecular Biology Education. 202149, 737-747. 

Overton, K.; Greer, H. M.; Ferguson, M. A.; Spain, E. M.; Elmore, D. E.; Núñez, M. E.; Volle, C. B.* "Qualitative and quantitative changes to Eschericihia coli during treatment with magainin 2 observed in native conditions by atomic force microscopy." Langmuir 202036:650-659.

Perez, C. P.; Elmore, D. E.; Rahakrishnan, M. L.* "Computationally modeling electrostatic binding energetics in a crowded, dynamic environment: Physical insights from a peptide-DNA system." J. Phys. Chem. B 2019123:10718-10734.

Wade, H. M.; Darling. L. E. O.; Elmore, D. E.* "Hybrids made from antimicrobial peptides with different mechanisms of action show enhanced membrane permeabilization." BBA—Biomembranes 20191861:182980.

Buck, A. K.; Elmore, D. E.; Darling, L. E. O.* "Using fluorescence microscopy to shed light on the mechanisms of antimicrobial peptides." Biochem. Mol. Biol. Educ. 201911:2445-2458.

Elmore, D. E. "It takes a village, but a village needs its leaders: An appreciation of Adele Wolfson." 201947:491-492.

Figueroa, D. M.Wade, H. M.Montales, K. P.; Elmore, D. E.*; Darling, L. E. O.*  “Production and visualization of bacterial spheroplasts and protoplasts to characterize antimicrobial peptide translocation.” Journal of Visualized Experiments. 2018, 138:57904.

Sim, S.Wang, P.Beyer, B. N.; Cutrona, K. J.; Radhakrishnan, M. L.; Elmore, D. E.*  “Investigating the nucleic acid interactions of histone-derived antimicrobial peptides.”  FEBS Lett.  2017591:706-717

Wei, L.LaBouyer, M. A.; Darling, L. E.*; Elmore, D. E.*  “Bacterial spheroplasts as a model for visualizing membrane translocation of antimicrobial peptides.”  Antimicrob. Agents Chemother.  201660:6350-6352.

Elmore, D. E.*  "Why should biochemistry students be introduced to molecular dynamics simulations--and how can we introduce them?"  Biochemistry and Molecular Biology Education  201644:118-123.

Cutrona, K. J.; Kaufman, B. A.Figueroa, D.; Elmore, D. E.*  “Role of arginine and lysine in the antimicrobial mechanism of histone-derived antimicrobial peptides.”  FEBS Lett.  2015589:3915-3920.

Malcolm, H. R.; Heo, Y.-Y.; Elmore, D. E.; Maurer, J. A.*  “Heteromultimerization of prokaryotic bacterial cyclic nucleotide gated (bCNG) ion channels, members of the mechanosensitive channel of small conductance (MscS) superfamily.”  Biochemistry.  201453:8005-8007.

Bustillo, M. E.+Fischer, A. L.+LaBouyer, M. A.Klaips, J. A.; Webb, A. C.; Elmore, D. E.*  “Modular analysis of hipposin, an antimicrobial peptide consisting of membrane translocating and membrane permeabilizing fragments.”  Invited article for Special Issue of BBA—Biomembranes.  20141838:2228-2233.

Elmore, D. E.*  "Insights into buforin II membrane translocation from molecular dynamics simulations."  Peptides.  201238:357-362.

Malcolm, H. R.; Heo, Y.-Y.; Caldwell, D. B.; McConnell, J. K.; Hawkins, J. F.Guayasamin, R. C.; Elmore, D. E.; Maurer, J. A.*  "Ss-bCNGa: a unique member of the bacterial cyclic nucleotide gated (bCNG) channel family that gates in response to mechanical tension."  Eur. Biophys. J.  2012, 41:1003-1013.

Pavia, K. E.+Spinella, S. A.+; Elmore, D. E.*  "Designed histone-derived antimicrobial peptides utilize different mechanisms of action."  BBA—Biomembranes.  20121818:869-876.

Malcolm, H. R.; Elmore, D. E.; Maurer, J. A.*  "Mechanosensitive behavior of bacterial cyclic nucleotide gated (bCNG) ion channels:  Insights into the mechanism of bCNG channel gating."  Biochem. Biophys. Res. Commun.  2012417:972-976.

Spinella, S. A.Nelson, R. B.; Elmore, D. E.*  "Measuring peptide translocation into large unilamellar vesicles."  Journal of Visualized Experiments.  Invited protocol. 2012, doi: 10.3791/3571

Malcolm, H. R.; Heo, Y.-Y.; Elmore, D. E.; Maurer, J. A.*  "Defining the role of the tension sensor in the mechanosensitive channel of small conductance (MscS)."  Biophys. J.2011101, 345-352.

Xie, Y.Fleming, E.Chen, J. L.; Elmore, D. E.*  "Effect of proline position on the antimicrobial mechanism of buforin II."  Peptides201132, 677-682.

Elmore, D. E.*  "Bringing ion channel crystal structures into sharper focus with computer modeling:  Examples from mechanosensitive channels."  Future Medicinal Chemistry.  20102, 909-913.  (Invited editorial.)

Caldwell, D. B.; Malcolm, H. R.; Elmore, D. E.*; Maurer, J. A.*  "Identification and experimental verification of a novel family of bacterial ligand-gated ion channels."  Biochimica Biophysica Acta—Biomembranes. 20101798, 1750-1756.

Elmore, D. E.*; Guayasamin, R. C.Kieffer, M. E.  "A series of molecular dynamics and homology modeling labs for an undergraduate course in molecular modeling."  Biochemistry and Molecular Biology Education.  201038, 216-223.

Tsao, H. S.Spinella, S. A.Lee, A. T.; Elmore, D. E.*  "Design of novel histone-derived antimicrobial peptides."  Peptides.  200930, 2168-2173.

Bruce, L. A.; Sigman, J. A.; Randall, D.; Rodriguez, S.; Song, M. M.Dai. Y.; Elmore, D. E.; Pabon, A.; Glucksman, M. J.; Wolfson, A. J.*  "Hydrogen bond residue positioning in the 599-611 loop of thimet oligopeptidase is required for substrate selection."  FEBS J.  2008275, 5607-5617.

Fleming, E.Maharaj, N. P.Chen, J. L.Nelson, R. B.; Elmore, D. E.*  "Effect of lipid composition on buforin II structure and membrane entry."  Proteins: Structure, Function, and Bioinformatics.  200873, 480-491.

Uyterhoeven, E. T.+; Butler, C. B.+; Ko, D.; Elmore, D. E.*  "Investigating the nucleic acid interactions and antimicrobial mechanism of buforin II."  FEBS Lett.  2008582, 1715-1718.

Maurer, J. A.+*; Elmore, D. E.+*; Clayton, D.; Xiong, L.; Lester, H. A.; Dougherty, D. A.  "Confirming the revised C-terminal domain of the MscL crystal structure."  Biophys. J.  200894, 4662-4667.

Elmore, D. E.*  Review of Computational Organic Chemistry by Steven M. Bachrach.  J. Am. Chem. Soc.  2007129, 14527-14528.

Spronk, S. A.; Elmore, D. E.; Dougherty, D. A.*  "Voltage-dependent hydration and conduction properties of the hydrophobic pore of the MscS channel."  Biophys. J.  200690, 3555-3569.

Elmore, D. E.*  "Molecular dynamics simulation of a phosphatidylglycerol membrane."  FEBS Lett.  2006580, 144-148.

Elmore, D. E.; Prentice, J. C.; Trosset, C.  "Do students understand liberal arts disciplines?"  Liberal Education.  200692, 48-55.